How can glucocorticoids benefit a pregnant woman with autoimmune disorders?

Glucocorticoids can benefit a pregnant woman with autoimmune disorders primarily by managing inflammation and immune responses. Autoimmune disorders are characterized by an overactive immune response where the body mistakenly attacks its own tissues. This can lead to significant inflammation, which may pose risks to both the mother and the developing fetus.

Use of glucocorticoids—in particular, their anti-inflammatory and immunosuppressive properties—can help regulate this immune activity, reducing the severity of the autoimmune response. This is crucial in improving the overall health of the pregnant woman and mitigating potential complications associated with uncontrolled inflammation, which can adversely affect pregnancy outcomes, including preterm birth, pregnancy loss, and fetal growth issues.

While glucocorticoids might have other effects, such as potentially influencing metabolic processes, their primary benefit in the context of autoimmune disorders during pregnancy is centered around their ability to modulate inflammation and the immune system effectively.