At what gestational week should Rho(D) immune globulin be administered to a Rh negative pregnant client suspected of sensitization?

Rho(D) immune globulin should be administered at 28 weeks of gestation to a Rh-negative pregnant client who is suspected of sensitization. This timing is critical because it helps prevent the development of Rh sensitization, which occurs when an Rh-negative individual is exposed to Rh-positive blood. Administering Rho(D) immune globulin at 28 weeks provides an effective prophylactic measure to minimize the risk of potential hemolytic disease of the newborn in future pregnancies.

The standard protocol includes giving Rho(D) immune globulin at this time, in addition to administering it following delivery if the newborn is confirmed to be Rh-positive. It is important for healthcare providers to adhere to this guideline to ensure the optimal health outcomes for both the mother and the baby. The 28-week schedule aligns with the common practice established by guidelines from organizations such as the American College of Obstetricians and Gynecologists (ACOG).